A crucial step in the development of new diagnostics devices, vaccines and antimicrobials depends of our ability to understand the complex molecular dynamics of pathogen evolution and the genomic components responsible for key biological processes responsible for invasion, replication, adaptation and dispersal.

To address these challenges my research focus in the development of algorithms for decoding genomic information of lethal viruses and bacteria and indentify genomic signatures that can be associated with pathogen source of origin, lethality and drug resistance.

Host-pathogen interactions occur at different temporal, spatial and molecular levels. Although far from complete, genome-wide molecular interactions are useful to understand the topological and dynamic features resulting from the direct interaction of the host with a particular pathogen. To tackle this problem I am leading the development of genomic analysis and data representation tools to indentify infection and exposure biomarkers using samples from humans and animal models exposed to different pathogens and toxins. Because these processes are complex and dynamic; another aspect of my research is to identify recognition sites that define virus and host interactions and therapeutic targets that modulate these processes.